Author

L. Coffman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. St. Croix· 2 shared N. Hempel· 2 shared S. C. Watkins· 2 shared Z. Javed· 2 shared A. E. Abdelnaby· 1 shared A. T. Elhaw· 1 shared A. T. Pearson· 1 shared C. Pressimone· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

C. St. Croix

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2 papers

Recent·Most cited

Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and cell fate in ovarian cancer.

Z. Javed, D. H. Shin, W. Pan, S. R. White, Y. S. Kim, A. T. Elhaw, S. Kamlapurkar, Y.-Y. Cheng, J. C. Benson, A. E. Abdelnaby, R. Phaeton, H.-G. Wang, S. Yang, M. L. G. Sullivan, C. St. Croix, , N. Hempel

This study identifies an alternative splice variant of Drp1 in ovarian cancer that promotes metastasis and chemoresistance by altering mitochondrial dynamics.

bioRxiv · Sep 20, 2023Cancer Biology

Carcinoma associated mesenchymal stem cells promote ovarian cancer metastasis by increasing tumor heterogeneity through direct mitochondrial transfer

C. Pressimone, L. G. Frisbie, E. Dyer, R. Baruwal, G. Gorecki, Z. Javed, C. St. Croix, S. C. Watkins, M. Calderon, H. I. Atiua, N. Hempel, A. T. Pearson, L. Coffman

This study shows carcinoma-associated mesenchymal stem cells promote ovarian cancer metastasis by transferring mitochondria to cancer cells, increasing tumor heterogeneity and enhancing survival.

bioRxiv · Sep 21, 2022 · PreprintCancer Biology