Cell BiologybioRxivPreprint
Epidermal Eg5 promotes X-ROS dependent paclitaxel neurotoxicity
A. C. Diaz, A. M. Cirrincione, N. A. Schmidt…·S. Rieger
The paper shows paclitaxel induces microtubule modifications in keratinocytes, leading to neurotoxicity via X-ROS and MMP-13, with Eg5 playing a key role.
DOI 10.1101/2023.05.22.541784