Author

S. Rieger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Animal Behavior & Cognition· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

T. S. Lisse· 4 shared A. D. Pellegrini· 2 shared A. M. Cirrincione· 2 shared E. Capobianco· 2 shared A. C. Diaz· 1 shared A. M. Cavanaugh· 1 shared A. Matynia· 1 shared A. Soliman· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCancer Biology

T. S. Lisse

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Epidermal Eg5 promotes X-ROS dependent paclitaxel neurotoxicity

A. C. Diaz, A. M. Cirrincione, N. A. Schmidt, M. J. Ugo, M. C. A. Sanchez, C. A. Reimonn, S. Wuchty, A. D. Pellegrini, L. R. Rude, L. G. Pappalardo, D. P. Regan, C. Howell, S. Hrstka, S. Dasari, T. S. Lisse, , S. Rieger

The paper shows paclitaxel induces microtubule modifications in keratinocytes, leading to neurotoxicity via X-ROS and MMP-13, with Eg5 playing a key role.

bioRxiv · May 22, 2023 · PreprintCell Biology

A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis

G. Luo, H. Kumar, K. Alridge, S. Rieger, E. Jiang, E. R. Chan, A. Soliman, H. Mahdi, J. J. Letterio

The paper defines a core NRF2 gene set from transcriptomic data that predicts drug resistance and poor cancer prognosis across multiple cancer types.

bioRxiv · Apr 20, 2023Cancer Biology

Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition

E. Capobianco, V. McGaughey, G. Seraphin, J. Heckel, S. Rieger, T. S. Lisse

This study shows vitamin D inhibits osteosarcoma by suppressing NMD, EMT, and ROS through VDR signaling and SNAI2 downregulation, with calcipotriol reducing metastasis in mice.

bioRxiv · Jan 4, 2023Cancer Biology

Vitamin D modulation of mitochondrial oxidative metabolism and mTOR enforces stress tolerance and anti-cancer responses

M. Quigley, S. Rieger, E. Capobianco, Z. Wang, H. Zhao, M. Hewison, T. S. Lisse

This study shows vitamin D reduces mitochondrial ROS and oxidative phosphorylation while enhancing stress tolerance and anti-cancer responses in osteosarcoma cells.

bioRxiv · Jun 8, 2021Cancer Biology

Short-wavelength violet light (420nm) stimulates melanopsin-dependent acute alertness responses in zebrafish

J. E. Contreras, T. S. Lisse, C. Bouzidi, A. M. Cavanaugh, A. Matynia, S. Rieger

This study identifies short-wavelength violet light-induced alertness responses in zebrafish, mediated by melanopsin and sympathetic circuits, with modulation by melatonin.

bioRxiv · Oct 31, 2019 · PreprintAnimal Behavior & Cognition

Paclitaxel-induced peripheral neuropathy is caused by epidermal ROS and mitochondrial damage through conserved MMP-13 activation

A. M. Cirrincione, S. Rieger, A. D. Pellegrini, J. Dominy, M. E. Benjamin, I. Utkina-Sosunova, F. Lotti, S. Jergova, J. Sagen

This study identifies epidermal ROS and mitochondrial damage as triggers of MMP-13 activation, leading to axon degeneration in paclitaxel-induced peripheral neuropathy.

bioRxiv · Sep 5, 2019Pathology