Author

A. D. Pellegrini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Cirrincione· 2 shared S. Rieger· 2 shared A. C. Diaz· 1 shared B. J. Harrison· 1 shared C. A. Reimonn· 1 shared C. Howell· 1 shared D. P. Regan· 1 shared F. Lotti· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

A. M. Cirrincione

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2 papers

Recent·Most cited

Epidermal Eg5 promotes X-ROS dependent paclitaxel neurotoxicity

A. C. Diaz, A. M. Cirrincione, N. A. Schmidt, M. J. Ugo, M. C. A. Sanchez, C. A. Reimonn, S. Wuchty, A. D. Pellegrini, L. R. Rude, L. G. Pappalardo, D. P. Regan, C. Howell, S. Hrstka, S. Dasari, T. S. Lisse, , S. Rieger

The paper shows paclitaxel induces microtubule modifications in keratinocytes, leading to neurotoxicity via X-ROS and MMP-13, with Eg5 playing a key role.

bioRxiv · May 22, 2023 · PreprintCell Biology

Paclitaxel-induced peripheral neuropathy is caused by epidermal ROS and mitochondrial damage through conserved MMP-13 activation

A. M. Cirrincione, S. Rieger, A. D. Pellegrini, J. Dominy, M. E. Benjamin, I. Utkina-Sosunova, F. Lotti, S. Jergova, J. Sagen

This study identifies epidermal ROS and mitochondrial damage as triggers of MMP-13 activation, leading to axon degeneration in paclitaxel-induced peripheral neuropathy.

bioRxiv · Sep 5, 2019Pathology