Author

L. Guidotti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Marotta· 2 shared E. Bono· 2 shared L. Donnici· 2 shared M. Iannacone· 2 shared M. Rava· 2 shared P. Di Lucia· 2 shared R. De Francesco· 2 shared S. Delbue· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

D. Marotta

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2 papers

Recent·Most cited

Nirmatrelvir treatment blunts the development of antiviral adaptive immune responses in SARS-CoV-2 infected mice

V. Fumagalli, P. Di Lucia, M. Rava, D. Marotta, E. Bono, S. Grassi, L. Donnici, R. Cannalire, I. Stefanelli, A. Ferraro, F. Esposito, E. Pariani, D. Inverso, C. Montesano, S. Delbue, , M. Iannacone

This study shows that nirmatrelvir treatment in SARS-CoV-2 infected mice reduces antibody and T cell responses, leading to weaker memory cell recruitment upon secondary challenge.

bioRxiv · Nov 22, 2022Immunology

Controlled administration of aerosolized SARS-CoV-2 to K18-hACE2 transgenic mice uncouples respiratory infection and anosmia from fatal neuroinvasion

V. Fumagalli, M. Rava, D. Marotta, P. Di Lucia, C. Laura, E. Sala, M. Grillo, E. Bono, L. Giustini, C. Perucchini, M. Mainetti, A. Sessa, J. Garcia-Manteiga, L. Donnici, L. Manganaro, , M. Iannacone

This study develops an aerosolized SARS-CoV-2 infection model in K18-hACE2 mice that replicates respiratory symptoms without fatal neuroinvasion, offering a more accurate representation of human COVID-19 pathogenesis.

bioRxiv · Aug 6, 2021Immunology