A Low-Dose Triple Antibody Cocktail Against the Ectodomain of the Matrix Protein 2 of Influenza A Is A Universally Effective and Viral Escape Mutant Resistant Therapeutic Agent
T. Kim, L. H. Bimler, S. L. Ronzulli, A. Y. Song, S. K. Johnson, C. A. Jones, S. M. Tompkins, S. Paust
This paper develops a low-dose triple antibody cocktail targeting the conserved M2e antigen of influenza A, showing universal efficacy and resistance to viral escape mutants in mouse models.
bioRxiv · Apr 2, 2022 · PreprintImmunology