IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α
E. Van Dis, H. M. Morrison, D. M. Fines, J. P. Babirye, L. H. McCann, S. Rawal, J. S. Cox, S. A. Stanley
This study identifies GM-CSF and HIF-1 activation as IFN-γ-independent mechanisms by which CD4 T cells control M. tuberculosis infection.
bioRxiv · Dec 16, 2021Immunology