MicrobiologybioRxiv
The roseoloviruses downregulate the protein tyrosine phosphatase PTPRC(CD45)
M. L. Whyte, K. A. Smith, A. Buchberger…·A. W. Hudson
This study identifies that HHV6A and HHV7 downregulate CD45 on T cells, impairing immune signaling and potentially promoting viral latency.
DOI 10.1128/jvi.01628-20