BiochemistrybioRxiv
Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3
L. Iglesias-Carres, S. A. Chadwick-Corbin, M. G. Sweet, A. P. Neilson
This study investigates whether chlorogenic acid and its metabolites inhibit hepatic FMO3-mediated conversion of TMA to TMAO, finding they do not at physiological or higher doses.
DOI 10.1016/j.jnutbio.2023.109428