Mucociliary Transport Deficiency and Disease Progression in Syrian Hamsters with SARS-CoV-2 Infection
Q. Li, K. Vijaykumar, S. Phillips, S. S. Hussain, V. N. Huynh, C. M. Fernandez-Petty, J. E. Peabody Lever, J. B. Foote, J. Ren, J. Campos-Gomez, F. A. Daya, N. W. Hubbs, H. Kim, E. Onuoha, E. R. Boitet, , S. M. Rowe
This study investigates MCT deficiency in Syrian hamsters infected with SARS-CoV-2, finding a 67% reduction in MCT rate by 2 dpi due to decreased motile ciliation.
bioRxiv · Jan 16, 2022Microbiology