MicrobiologybioRxiv
Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity
C. B. Lopez, L. J. Gonzalez Aparicio, Y. Yang, M. S. Hackbart
This study shows that copy-back viral genomes (cbVGs) induce cellular stress responses, including stress granules and translation inhibition, during RSV and parainfluenza virus infections, which reduce viral protein expression without affecting antiviral immunity.
DOI 10.1371/journal.pbio.3002381