Diverse Streptococcus pneumoniae strains drive a MAIT cell response through MR1-dependent and cytokine-driven pathways
A. Kurioka, B. van Wilgenburg, R. R. Javan, R. Hoyle, A. J. van Tonder, C. L. Harrold, T. Leng, L. J. Howson, D. Shepherd, V. Cerundolo, A. B. Brueggemann, P. Klenerman
This study shows that diverse Streptococcus pneumoniae strains activate MAIT cells via MR1-dependent and cytokine-driven pathways, with conserved riboflavin operon genes across strains.
bioRxiv · Jul 17, 2017Immunology