Author

L. J. N. Cooper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

N. Varadarajan· 3 shared A. Leekha· 2 shared A. Saeedi· 2 shared B. L. Hurst· 2 shared M. Fathi· 2 shared M. Kumar· 2 shared M. M. Paniagua· 2 shared M. Sebastian· 2 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

N. Varadarajan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ending transmission of SARS-CoV-2: sterilizing immunity using an intranasal subunit vaccine

A. Leekha, A. Saeedi, S. R. Sefat, M. Kumar, M. M. Paniagua, A. Damian, R. Kulkarni, A. Rezvan, S. Mosoumi, X. Liu, L. J. N. Cooper, M. Sebastian, B. L. Hurst, N. Varadarajan

This paper develops an intranasal multi-antigen vaccine that prevents SARS-CoV-2 infection and transmission by targeting both spike and nucleocapsid proteins.

bioRxiv · Jul 14, 2022Immunology

An intranasal nanoparticle STING agonist has broad protective immunity against respiratory viruses and variants

A. Leekha, A. Saeedi, M. Kumar, S. R. Sefat, M. M. Paniagua, M. Fathi, R. Kulkarni, S. Biswas, D. Tsitoura, X. Liu, L. J. N. Cooper, M. Sebastian, B. L. Hurst, N. Varadarajan

This study develops NanoSTING, an intranasal nanoparticle STING agonist, showing broad protection against respiratory viruses and variants in animal models.

bioRxiv · Apr 18, 2022Immunology

Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers

M. Fathi, L. Charley, L. J. N. Cooper, N. Varadarajan, D. Meyer

This study uses time-lapse imaging and machine learning to show that SARS-CoV-2-specific cytotoxic T cells can kill multiple infected targets, highlighting their potential for broad immunity.

bioRxiv · Jan 24, 2022Immunology