Author

A. Leekha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Saeedi· 3 shared N. Varadarajan· 3 shared A. Rezvan· 2 shared B. L. Hurst· 2 shared L. J. N. Cooper· 2 shared M. Fathi· 2 shared M. Kumar· 2 shared M. M. Paniagua· 2 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Saeedi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineering non-cytotoxic delivery of proteins by T cells via fusion to NPC2

A. Saeedi, I. N. Bandey, A. Leekha, M. Fathi, A. Rezvan, M. J. Montalvo, K.-L. Wu, R. Bohat, W. Peng, N. Varadarajan

This study demonstrates that fusing proteins to NPC2 enables non-cytotoxic protein delivery by T cells through the perforin pathway.

bioRxiv · Sep 24, 2022 · PreprintImmunology

Ending transmission of SARS-CoV-2: sterilizing immunity using an intranasal subunit vaccine

A. Leekha, A. Saeedi, S. R. Sefat, M. Kumar, M. M. Paniagua, A. Damian, R. Kulkarni, A. Rezvan, S. Mosoumi, X. Liu, L. J. N. Cooper, M. Sebastian, B. L. Hurst, N. Varadarajan

This paper develops an intranasal multi-antigen vaccine that prevents SARS-CoV-2 infection and transmission by targeting both spike and nucleocapsid proteins.

bioRxiv · Jul 14, 2022Immunology

An intranasal nanoparticle STING agonist has broad protective immunity against respiratory viruses and variants

A. Leekha, A. Saeedi, M. Kumar, S. R. Sefat, M. M. Paniagua, M. Fathi, R. Kulkarni, S. Biswas, D. Tsitoura, X. Liu, L. J. N. Cooper, M. Sebastian, B. L. Hurst, N. Varadarajan

This study develops NanoSTING, an intranasal nanoparticle STING agonist, showing broad protection against respiratory viruses and variants in animal models.

bioRxiv · Apr 18, 2022Immunology