Author

L. K. Brents

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. J. Parks· 2 shared G. S. Gorman· 2 shared P. Salazar· 2 shared A. W. Alund· 1 shared E. C. Peterson· 1 shared J. H. Moran· 1 shared J. Tobacyk· 1 shared L. Coward· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

B. J. Parks

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2 papers

Recent·Most cited

Interaction between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome.

J. Tobacyk, B. J. Parks, P. Salazar, L. Coward, M. D. Berquist, G. S. Gorman, L. K. Brents

This study investigates the interaction between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome, finding that NorBUP contributes more to NOWS in females than males.

bioRxiv · Dec 27, 2022Pharmacology & Toxicology

Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats

V. Janganati, P. Salazar, B. J. Parks, G. S. Gorman, P. L. Prather, E. C. Peterson, A. W. Alund, J. H. Moran, P. A. Crooks, L. K. Brents

This study shows that deuterated buprenorphine (BUP-D2) retains pharmacodynamic properties of buprenorphine and significantly reduces metabolism to the active metabolite norbuprenorphine in rats.

bioRxiv · Dec 12, 2022Pharmacology & Toxicology