Author

G. S. Gorman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:rat· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. J. Parks· 2 shared L. K. Brents· 2 shared P. Salazar· 2 shared A. B. Keeton· 1 shared A. B. Ward· 1 shared A. K. Mitra· 1 shared A. W. Alund· 1 shared B. F. El-Rayes· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPharmacology & Toxicology

B. J. Parks

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer

J. Foote, T. E. Mattox, A. B. Keeton, X. Chen, F. T. Smith, K. L. Berry, T. W. Holmes, J. Wang, C.-H. Wang, A. B. Ward, A. K. Mitra, V. R. Alcantara, C. Hardy, K. G. Fleten, K. Flatmark, , G. A. Piazza

This paper introduces ADT-007, a novel pan-RAS inhibitor that effectively blocks tumor growth in mouse models of GI cancer by targeting RAS activation and inducing apoptosis.

bioRxiv · May 17, 2023 · PreprintCancer Biology

Interaction between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome.

J. Tobacyk, B. J. Parks, P. Salazar, L. Coward, M. D. Berquist, G. S. Gorman, L. K. Brents

This study investigates the interaction between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome, finding that NorBUP contributes more to NOWS in females than males.

bioRxiv · Dec 27, 2022Pharmacology & Toxicology

Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats

V. Janganati, P. Salazar, B. J. Parks, G. S. Gorman, P. L. Prather, E. C. Peterson, A. W. Alund, J. H. Moran, P. A. Crooks, L. K. Brents

This study shows that deuterated buprenorphine (BUP-D2) retains pharmacodynamic properties of buprenorphine and significantly reduces metabolism to the active metabolite norbuprenorphine in rats.

bioRxiv · Dec 12, 2022Pharmacology & Toxicology