L. Kalan

Still Not Sterile: Chlorhexidine gluconate treatment does not completely reduce skin microbial bioburden and promotes pathogen overabundance in patients undergoing elective surgeries.

This study shows that chlorhexidine gluconate reduces viable skin microbial bioburden but does not achieve complete sterility, and temporarily increases pathogen abundance before microbiome recovery.

Skin-associated Corynebacterium amycolatum shares cobamides

This study shows that Corynebacterium amycolatum produces cobamides and shares them with E. coli, supporting its growth through cobamide synthesis and spatial separation.

What is Slough?A pilot study to define the proteomic and microbial composition of wound slough and its implications for wound healing.

This study characterizes the proteomic and microbial composition of wound slough and integrates these with clinical data to predict wound healing outcomes.

Comparative genomic and metagenomic investigations of the Corynebacterium tuberculostearicum species complex reveals potential mechanisms underlying associations to skin health and disease

The paper investigates the Corynebacterium tuberculostearicum species complex using genomic and metagenomic analyses to identify traits associated with skin health and disease.

Sweat and sebum preferences of the human skin microbiota

This study investigates how human skin bacteria prefer sweat and sebum, showing most prefer high sweat concentrations while sebum preference varies, influencing microbial community structure.

Trade-offs between antiseptic cytotoxicity and efficacy in a human ex vivo wound contamination model

The paper evaluates the cytotoxicity and efficacy of five antiseptics in an ex vivo human wound model, finding chlorhexidine gluconate reduces microbial counts but harms tissue viability.

Cobamide sharing drives skin microbiome dynamics

This study shows cobamide sharing shapes skin microbiome networks, with Corynebacterium species driving community structure and diversity through cobamide production.

Effects of Topical Antimicrobial Formulations on Pseudomonas aeruginosa Biofilm in an In vivo Porcine Burn Wound Model

This study evaluates the effectiveness of different silver-based wound dressings in reducing Pseudomonas aeruginosa biofilms in a porcine burn wound model, finding that silver oxynitrate powder most effectively reduced bacterial counts.