Author

L. Karlsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

A. J. Arribas· 1 shared A. K. Hilli· 1 shared A. R. Mato· 1 shared A. Urban· 1 shared E. Normant· 1 shared F. Bertoni· 1 shared G. E. Tjonnfjord· 1 shared I. Murali· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. J. Arribas

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1 paper

Recent·Most cited

Functional testing of PI3K inhibitors stratifies responders to idelalisib and identifies treatment vulnerabilities in idelalisib-refractory/intolerant chronic lymphocytic leukemia

Y. Yin, P. Athanasiadis, L. Karlsen, A. Urban, I. Murali, S. M. Fernandes, A. J. Arribas, A. K. Hilli, K. Tasken, F. Bertoni, A. R. Mato, E. Normant, J. R. Brown, G. E. Tjonnfjord, T. Aittokallio, S. S. Skanland

This study uses ex vivo drug sensitivity testing to identify treatment responses and vulnerabilities in chronic lymphocytic leukemia patients, showing that pan-PI3Ki and combinations with venetoclax can be effective in idelalisib-refractory/intolerant cases.

bioRxiv · Apr 14, 2022 · PreprintCancer Biology