Human Cytomegalovirus uses a Host Stress Response to Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very Long Chain Fatty Acids
Y. Xi, L. Lindenmayer, I. Kline, J. von Einem, J. G. Purdy
This study shows that PERK, part of the ER stress pathway, differentially regulates fatty acid elongation enzymes to balance lipid synthesis in HCMV-infected cells, supporting viral replication.
bioRxiv · Jan 16, 2021Microbiology