Author

J. von Einem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:deep learning· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Read· 2 shared A. R. Rep· 1 shared B. G. Butt· 1 shared C. C. Nguyen· 1 shared C. M. Hall· 1 shared C. Shang· 1 shared D. Fischer· 1 shared H. Zhang· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

C. Read

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3 papers

Recent·Most cited

Human cytomegalovirus deploys molecular mimicry to recruit VPS4A to sites of virus assembly

B. G. Butt, D. Fischer, A. R. Rep, M. Schauflinger, C. Read, T. Bock, M. Hirner, S. C. Graham, J. von Einem

This study identifies a viral motif in pUL71 that mimics cellular ESCRT-III components to recruit VPS4A to the HCMV assembly site, though its functional role remains unclear.

bioRxiv · Jan 4, 2024Cell Biology

Human Cytomegalovirus uses a Host Stress Response to Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very Long Chain Fatty Acids

Y. Xi, L. Lindenmayer, I. Kline, J. von Einem, J. G. Purdy

This study shows that PERK, part of the ER stress pathway, differentially regulates fatty acid elongation enzymes to balance lipid synthesis in HCMV-infected cells, supporting viral replication.

mBio · Jun 29, 2021Peer-reviewedMicrobiology

A cytomegalovirus immunevasin triggers integrated stress response-dependent reorganization of the endoplasmic reticulum.

H. Zhang, C. Read, C. C. Nguyen, M. N. A. Siddiquey, C. Shang, C. M. Hall, J. von Einem, J. P. Kamil

This paper shows that HCMV's UL148 protein reorganizes the ER via the integrated stress response, affecting viral infectivity and immune evasion.

bioRxiv · Aug 17, 2019 · PreprintMicrobiology