Author

L. M. Cook

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

C. Morrissey· 2 shared A. J. Dafferner· 1 shared A. M. Bhat· 1 shared A. Natarajan· 1 shared B. A. Teply· 1 shared B. C. Mohapatra· 1 shared B. Nolan· 1 shared D. Costanzo-Garvey· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

C. Morrissey

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior

A. M. Bhat, B. C. Mohapatra, H. Luan, I. Mushtaq, S. Chakraborty, S. Kumar, W. Wu, B. Nolan, S. Dutta, M. D. Stock, M. Schott, J. L. Meza, S. M. Lele, M.-F. Lin, L. M. Cook, , H. Band

This study shows GD2 and its biosynthetic enzyme GD3S promote prostate cancer tumorigenesis by maintaining cancer stem cells and EMT markers.

bioRxiv · Mar 18, 2023Cancer Biology

Androgen-mediated TGFβ expression suppresses anti-tumor neutrophil response in bone metastatic prostate cancer

M. Alsamraae, D. Costanzo-Garvey, B. A. Teply, S. Boyle, G. Sommerville, Z. Herbert, C. Morrissey, A. J. Dafferner, M. Y. Abdalla, R. W. Fallet, T. Kielian, H. Jensen-Smith, E. I. deOliveira, K. Chen, I. A. Bettencourt, , L. M. Cook

This study identifies androgen-mediated TGFβ expression as a mechanism suppressing anti-tumor neutrophil response in bone metastatic prostate cancer and shows that combining ADT with TGFβ receptor inhibition restores neutrophil cytotoxicity.

bioRxiv · Dec 30, 2022 · PreprintCancer Biology