Cancer BiologybioRxiv
Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier
N. L. Tran, L. M. Ferreira, B. Alvarez-Moya…·G. Sitia
The paper shows that continuous IFNα infusion reduces CRC liver metastasis by acting on hepatic endothelial cells to create an antimetastatic vascular barrier.
DOI 10.7554/elife.80690