Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State
B. Svensson, F. R. Nitu, R. T. Rebbeck, L. M. McGurran, T. Oda, D. D. Thomas, D. M. Bers, R. L. Cornea
This paper uses FRET to study how DPc10 and CaM interact with RyR2, revealing their distinct effects on channel function and structural changes.
bioRxiv · Jul 7, 2023 · PreprintBiophysics