Author

L. M. T. Lima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

T. Sisnande· 3 shared C. K. Lima· 1 shared C. Sinezia· 1 shared D. C. Da Silva· 1 shared D. O. Matias· 1 shared F. L. Brum· 1 shared F. S. Ribeiro· 1 shared L. Miranda-Alves· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

T. Sisnande

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Author profile →

3 papers

Recent·Most cited

Oral delivery of the amylin receptor agonist pramlintide

C. Sinezia, T. Sisnande, L. P. Icart, L. M. T. Lima

This study develops and characterizes polymeric microparticles for oral delivery of pramlintide, showing prolonged release compared to intravenous administration.

bioRxiv · Nov 9, 2023Pharmacology & Toxicology

Spatially resolved distribution of pancreatic hormones proteoforms by MALDI-imaging mass spectrometry

T. Sisnande, F. L. Brum, D. O. Matias, F. S. Ribeiro, T. B. Moulin, R. S. Mohana-Borges, M. T. Magalhaes, L. M. T. Lima

The paper uses MALDI-imaging mass spectrometry to analyze pancreatic hormone proteoforms in mice, showing reduced peptide intermediates under zinc restriction.

bioRxiv · Oct 27, 2023Biochemistry

Zinc restriction promotes β-cell hyper-hormonemia and endocrine pancreas degeneration in mice

T. Sisnande, C. K. Lima, D. C. Da Silva, T. M. Beninatto, N. L. Alves, M. J. Amaral, L. Miranda-Alves, L. M. T. Lima

This study shows that zinc restriction in mice leads to increased β-cell hormone levels and pancreatic islet degeneration despite reduced islet size.

bioRxiv · Apr 23, 2019 · PreprintBiochemistry