Author

L. Malouf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:biophysical modeling· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

L. Di Michele· 2 shared A. Huyghebaert· 1 shared A. Leathers· 1 shared D. A. Tanase· 1 shared D. M. Vadukul· 1 shared D. Tanase· 1 shared F. A. Aprile· 1 shared F. Raguseo· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

L. Di Michele

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Sculpting DNA-based synthetic cells through phase separation and phase-targeted activity

L. Malouf, D. A. Tanase, G. Fabrini, M. Paez-Perez, A. Leathers, M. J. Booth, L. Di Michele

This paper demonstrates the creation of synthetic cells using DNA nanostructures that form compartmentalized architectures with targeted activities through phase separation and chemical modifications.

bioRxiv · Mar 17, 2023Biophysics

The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes

F. Raguseo, A. Huyghebaert, J. Li, R. Balendra, m. Petric Howe, Y. Wang, D. M. Vadukul, D. Tanase, T. E. Maher, L. Malouf, R. Rubio Sanchez, F. A. Aprile, Y. Elani, R. Patani, L. Di Michele, M. Di Antonio

This study shows that C9orf72 hexanucleotide repeat expansions form RNA condensates via multimolecular G-quadruplexes, suggesting a therapeutic target for ALS/FTD.

bioRxiv · Jan 31, 2023Biochemistry