Author

Y. Elani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Y. Wang· 2 shared A. Huyghebaert· 1 shared A. Marzook· 1 shared A. Oishi· 1 shared A. Tomas· 1 shared B. Jones· 1 shared D. Hodson· 1 shared D. M. Vadukul· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Y. Wang

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2 papers

Recent·Most cited

The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes

F. Raguseo, A. Huyghebaert, J. Li, R. Balendra, m. Petric Howe, Y. Wang, D. M. Vadukul, D. Tanase, T. E. Maher, L. Malouf, R. Rubio Sanchez, F. A. Aprile, Y. Elani, R. Patani, L. Di Michele, M. Di Antonio

This study shows that C9orf72 hexanucleotide repeat expansions form RNA condensates via multimolecular G-quadruplexes, suggesting a therapeutic target for ALS/FTD.

bioRxiv · Jan 31, 2023Biochemistry

Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking

M. Lucey, T. Ashik, A. Marzook, Y. Wang, J. Goulding, A. Oishi, J. Broichhagen, D. Hodson, J. Minnion, Y. Elani, R. Jockers, S. J. Briddon, S. R. Bloom, A. Tomas, B. Jones

This study compares exendin-4 and its acylated variant exendin-4-C16, showing acylation affects GLP-1R signaling bias, trafficking, and pharmacokinetics.

bioRxiv · Apr 1, 2021Pharmacology & Toxicology