L. Mancini

Surface versus volume synthesis governs growth-dependent efficacy of a β-lactam antibiotic

This study shows that mecillinam affects the balance between surface area and volume synthesis in E. coli, leading to growth-rate dependent efficacy and lysis or sustained growth depending on the medium.

Multipad Agarose Plate (MAP): A Rapid and High-Throughput Approach for Antibiotic Susceptibility Testing

The paper introduces a high-throughput antibiotic susceptibility testing method using a Multipad Agarose Plate that reduces turnaround time by eightfold.

Environmental conditions define theenergetics of bacterial dormancy and itsantibiotic susceptibility

The paper investigates how environmental conditions affect the energy states of dormant bacterial cells and their susceptibility to antibiotics.

Coordination of gene expression with cell size enables Escherichia coli to efficiently maintain motility across conditions

This study shows E. coli upregulates motility genes at slow growth to maintain flagella number and motility, while larger cell size at fast growth optimizes resource allocation.

In vitro selection of a microbial consortium predictive of synergistic functioning along multiple ecosystem scales

The paper assesses how different microbial consortia affect phosphorus solubilization and plant growth, finding that combined species outperform individual species.

Escherichia coli’s physiology can turn membrane voltage dyes into actuators

The paper develops a workflow to characterize Nernstian membrane voltage dyes in E. coli, identifying conditions where dyes act as actuators rather than probes.