Author

L. Marx

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

E. F. Semeraro· 2 shared G. Pabst· 2 shared H. Bergler· 2 shared J. Mandl· 2 shared K. Lohner· 2 shared S. Prevost· 2 shared Abbe LaiiD· 1 shared Alissa M. D’GamaiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

E. F. Semeraro

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3 papers

Recent·Most cited

Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy

Sattar Khoshkhoo, Mingyun Bae, Yilan Wang, Ashton Tillett, Rosita B. Ramirez, Benjamin Finander, Emily D. Egan, L. Marx, Dipan Patel, Zinan Zhou, Yasmine Chahine, Brian H. Chhouk, Sofía Zoullas, Abbe Lai, Roland Coras, , Christopher A. Walsh

This study identifies somatic Ras-MAPK pathway variants in hippocampal tissue from patients with drug-resistant epilepsy, showing their association with clonal competition and worse surgical outcomes.

bioRxiv · Jan 27, 2026 · PreprintGenetics

Lactoferricins access the cytosol of Escherichia coli within few seconds

E. F. Semeraro, L. Marx, J. Mandl, I. Letofsky-Papst, C. Mayrhofer, M. P. K. Frewein, H. L. Scott, S. Prevost, H. Bergler, K. Lohner, G. Pabst

This study shows lactoferricin-derived AMPs rapidly enter E. coli cytosol within seconds, leading to metabolic shutdown, with membrane damage being a secondary effect.

bioRxiv · Sep 24, 2021 · PreprintBiophysics

Evolution of the Analytical Scattering Model of Live Escherichia Coli

E. F. Semeraro, L. Marx, J. Mandl, M. Frewein, H. Scott, S. Prevost, H. Bergler, K. Lohner, G. Pabst

The paper revises a scattering model for live E. coli to better fit experimental data and reveals structural differences between strains.

bioRxiv · Sep 18, 2020Biophysics