Author

Yasmine Chahine

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Christopher A. WalshiD· 2 shared Eunjung Alice LeeiD· 2 shared Abbe LaiiD· 1 shared Alexej S. AbyzoviD· 1 shared Alissa M. D’GamaiD· 1 shared Amy E Roberts· 1 shared Andrew Gao· 1 shared Andrew J. ChessiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Christopher A. WalshORCID

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2 papers

Recent·Most cited

Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy

Sattar Khoshkhoo, Mingyun Bae, Yilan Wang, Ashton Tillett, Rosita B. Ramirez, Benjamin Finander, Emily D. Egan, L. Marx, Dipan Patel, Zinan Zhou, Yasmine Chahine, Brian H. Chhouk, Sofía Zoullas, Abbe Lai, Roland Coras, , Christopher A. Walsh

This study identifies somatic Ras-MAPK pathway variants in hippocampal tissue from patients with drug-resistant epilepsy, showing their association with clonal competition and worse surgical outcomes.

bioRxiv · Jan 27, 2026 · PreprintGenetics

Enrichment of somatic mutations in schizophrenia brain targets prenatally active transcription factor bindings sites

Eduardo A. Maury, Attila Jones, Vladimir B. Seplyarskiy, Chaggai Rosenbluh, Taejeong Bae, Yifan Wang, Alexej S. Abyzov, Sattar Khoshkoo, Yasmine Chahine, Brain Somatic Mosaicism Network, Peter J. Park, Schahram Akbarian, Eunjung Alice Lee, Shamil R. Sunyaev, Christopher A. Walsh, Andrew J. Chess

The paper identifies prenatal mutational processes in schizophrenia brains linked to transcription factor binding sites and proposes a new term 'skiagenesis' for these mutations.

bioRxiv · Feb 23, 2022 · PreprintGenomics