Author

Ashton Tillett

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alissa M. D’GamaiD· 2 shared Annapurna PoduriiD· 2 shared August Yue HuangiD· 2 shared Benjamin FinanderiD· 2 shared Brian H. ChhoukiD· 2 shared Christopher A. WalshiD· 2 shared Edward YangiD· 2 shared Ingmar BlümckeiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Alissa M. D’GamaORCID

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2 papers

Recent·Most cited

Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy

Sattar Khoshkhoo, Mingyun Bae, Yilan Wang, Ashton Tillett, Rosita B. Ramirez, Benjamin Finander, Emily D. Egan, L. Marx, Dipan Patel, Zinan Zhou, Yasmine Chahine, Brian H. Chhouk, Sofía Zoullas, Abbe Lai, Roland Coras, , Christopher A. Walsh

This study identifies somatic Ras-MAPK pathway variants in hippocampal tissue from patients with drug-resistant epilepsy, showing their association with clonal competition and worse surgical outcomes.

bioRxiv · Jan 27, 2026 · PreprintGenetics

Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs

Sara Bizzotto, Maya Talukdar, Edward Stronge, Rosita B. Ramirez, Yingxi Yang, August Yue Huang, Qiwen Hu, Yingping Hou, Norma K. Hylton, Benjamin Finander, Ashton Tillett, Zinan Zhou, Brian H. Chhouk, Alissa M. D’Gama, Edward Yang, , Christopher A. Walsh

This study uses snRNA-seq and a new method called GO-TEN to analyze mosaic genetic variants in focal cortical dysplasia, revealing cell-autonomous and non-cell-autonomous transcriptional changes associated with epilepsy.

Proceedings of the National Academy of Sciences · Jul 17, 2025Peer-reviewedGenetics