Author

L. Melcher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Bruder· 2 shared A. Jeron· 1 shared A. Kroeger· 1 shared A. M. Kempf· 1 shared E. Gelmez· 1 shared F. Miller· 1 shared H. Jacobsen· 1 shared I. Nehlmeier· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

D. Bruder

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Epigenetic changes and serotype-specific interferon-responses of lung epithelial cells in late post-influenza pneumococcal pneumonia

J. D. Boehme, A. Jeron, K. Schultz, L. Melcher, K. Schott, E. Gelmez, A. Kroeger, S. Stegemann-Koniszewski, D. Bruder

This study investigates how IAV infection alters the transcriptional and epigenetic responses of lung epithelial cells to pneumococcal serotypes, revealing serotype-specific interferon responses and epigenetic changes.

bioRxiv · Jun 28, 2023 · PreprintImmunology

TMPRSS2 is essential for SARS-CoV-2 Beta and Omicron infection

K. Metzdorf, H. Jacobsen, M. C. Greweling-Pils, M. Hoffmann, T. Lueddecke, F. Miller, L. Melcher, A. M. Kempf, I. Nehlmeier, D. Bruder, M. Widera, S. Ciesek, S. Poehlmann, L. Cicin-Sain

The paper shows TMPRSS2 is essential for SARS-CoV-2 Beta and Omicron infection in mice, highlighting its role as an antiviral target.

bioRxiv · Dec 9, 2022Immunology