TMPRSS2 is essential for SARS-CoV-2 Beta and Omicron infection
K. Metzdorf, H. Jacobsen, M. C. Greweling-Pils, M. Hoffmann, T. Lueddecke, F. Miller, L. Melcher, A. M. Kempf, I. Nehlmeier, D. Bruder, M. Widera, S. Ciesek, S. Poehlmann, L. Cicin-Sain
The paper shows TMPRSS2 is essential for SARS-CoV-2 Beta and Omicron infection in mice, highlighting its role as an antiviral target.
bioRxiv · Dec 9, 2022Immunology