Structure, dynamics, and inhibition of Staphylococcus aureus m1A22-tRNA methyltransferase
P. Sweeney, A. Crowe, A. Kumar, D. Raju, N. B. Krishna, E. Sutherland, C. J. Leo, G. Fisher, R. Lalitha, L. Muthuraj, G. Sigamani, V. Oehler, S. Synowsky, S. L. Shirran, T. M. Gloster, , R. G. da Silva
This study characterizes the structure, dynamics, and inhibition of Staphylococcus aureus TrmK, identifying a cryptic binding pocket for drug discovery.
bioRxiv · Dec 24, 2021 · PreprintBiochemistry