This study characterizes the structure, dynamics, and inhibition of Staphylococcus aureus TrmK, identifying a cryptic binding pocket for drug discovery.

bioRxiv · Dec 24, 2021 · PreprintBiochemistry

BioSkills Guide: Development and National Validation of a Tool for Interpreting the Vision and Change Core Competencies

A. Clemmons, J. Timbrook, J. Herron, A. Crowe

The paper develops and validates the BioSkills Guide, a tool for interpreting Vision and Change core competencies, through input from over 250 institutions and a national survey of educators.

bioRxiv · Jan 11, 2020Scientific Communication & Education

Dominance of ST131 Escherichia coli carrying blaCTX-M in patients with bloodstream infections caused by cephalosporin-resistant strains in Australia, New Zealand and Singapore: whole genome analysis of isolates from a randomised trial

P. Harris, N. Ben Zakour, L. W. Roberts, A. M. Wailan, H. M. Zowawi, P. A. Tambyah, D. C. Lye, R. Jureen, T. H. Lee, E. Izharuddin, M. Yin, D. Looke, N. Runnegar, B. Rogers, H. Bhally, , D. L. Paterson

The paper characterizes multidrug-resistant Escherichia coli from bloodstream infections in Australia, New Zealand, and Singapore, finding ST131 dominates with blaCTX-M ESBLs, particularly blaCTX-M-15.

bioRxiv · Aug 29, 2017Microbiology