Author

L. O'Driscoll

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. A. Hoey· 3 shared I. Woods· 3 shared K. Eichholz· 3 shared M. Lowery· 2 shared N. Shen· 2 shared A. Federici· 1 shared B. D. Henderson· 1 shared E. Oner· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioengineering

D. A. Hoey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

V. M. Saini, E. Oner, M. Ward, S. Hurley, B. D. Henderson, F. Lewis, S. P. Finn, J. O'Leary, S. O'Toole, L. O'Driscoll, K. Gately

This study compares five CTC isolation technologies in lung cancer, finding CellMag and Parsortix PR1 have the highest recovery rates.

bioRxiv · Feb 5, 2024Cancer Biology

Mechanically activated bone cells drive vessel formation via an extracellular vesicle mediated mechanism

N. Shen, M. Maggio, I. Woods, K. Eichholz, E. Stavenschi, M. Lowery, F. M. Roche, K. Hokamp, L. O'Driscoll, D. A. Hoey

This study shows mechanically activated bone cells promote vessel formation through extracellular vesicles, which contain miRNAs linked to angiogenesis, offering a potential therapeutic for bone repair.

bioRxiv · Feb 10, 2023 · PreprintBioengineering

Mechanically Activated Extracellular Vesicle Functionalised Melt Electrowritten Materials for Bone Regeneration: A Mechano-Biomimetic Scaffold

K. Eichholz, A. Federici, M. Riffault, I. Woods, O. Mahon, L. O'Driscoll, D. A. Hoey

This study develops a mechano-biomimetic scaffold combining MEW scaffolds with mechanically activated osteocyte-derived EVs to enhance bone regeneration.

bioRxiv · Mar 29, 2021 · PreprintBioengineering

Human bone marrow mesenchymal stem/stromal cell behaviour is coordinated via mechanically activated osteocyte-derived extracellular vesicles

K. Eichholz, I. Woods, G. Johnson, N. Shen, M. Corrigan, M.-N. Labour, K. Wynne, M. Lowery, L. O'Driscoll, D. A. Hoey

This study shows that mechanically activated osteocyte-derived extracellular vesicles enhance human MSC recruitment and osteogenesis, suggesting their potential as a cell-free therapy for bone regeneration.

bioRxiv · Aug 8, 2019 · PreprintPhysiology