Cancer BiologybioRxiv
ImmunoPET as Stoichiometric Sensor for Glypican-3 in Models of Hepatocellular Carcinoma
O. J. Kelada, N. T. Gutsche, M. Bell…·F. E. Escorcia
This paper demonstrates that the immunoPET agent [89Zr]Zr-DFO-TAB-H14 specifically and stoichiometrically binds to GPC3 in human liver cancer models, serving as a potential in vivo sensor for HCC diagnosis and therapy selection.