NuMA is a negative regulator of 53BP1 in DNA double-strand break repair
N. Salvador-Moreno, J. Liu, K. Haas, L. Parker, C. Chakraborty, S. Kron, K. Hodges, L. Miller, P. Robinson, S. Lelievre, P.-A. Vidi
This study identifies NuMA as a negative regulator of 53BP1, showing it prevents 53BP1 accumulation at DNA breaks and influences repair outcomes.
bioRxiv · Dec 7, 2017Cell Biology