Gene knockout shows that PML (TRIM19) does not restrict the early stages of HIV-1 infection in human cell lines
N. Masroori, P. Cherry, N. Merindol, J.-x. Li, C. Dufour, L. Poulain, M. B. Plourde, L. Berthoux
This paper uses CRISPR-Cas9 to knockout PML in human cell lines and shows it does not restrict early HIV-1 infection or IFN-I-mediated inhibition.
bioRxiv · May 21, 2017Immunology