Author

L. R. Chiarelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Ras· 1 shared E. Deziel· 1 shared F. Manetti· 1 shared G. Degiacomi· 1 shared G. Stelitano· 1 shared H. Gasparovic· 1 shared J. C. Sammartino· 1 shared J. Kordulakova· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

C. Ras

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2 papers

Recent·Most cited

The veterinary anti-parasitic selamectin is a novel inhibitor of the mycobacterial DprE1 enzyme

J. M. Ezquerra-Aznarez, G. Degiacomi, H. Gasparovic, G. Stelitano, J. C. Sammartino, J. Kordulakova, P. Governa, F. Manetti, M. R. Pasca, L. R. Chiarelli, S. Ramon-Garcia

This study identifies selamectin as an inhibitor of the mycobacterial DprE1 enzyme, showing susceptibility in mutants and docking predictions, but with conflicting results in phenotypic assays and metabolic labeling.

bioRxiv · Dec 4, 2021 · PreprintMicrobiology

Phenylacetyl-CoA, not phenylacetic acid, attenuates CepIR-regulated virulence in Burkholderia 2 cenocepacia

T. J. Lightly, K. L. Frejuk, M.-C. Groleau, L. R. Chiarelli, C. Ras, S. Buroni, E. Deziel, J. L. Sorensen, S. T. Cardona

The paper shows that phenylacetyl-CoA, not phenylacetic acid, suppresses virulence in Burkholderia cenocepacia by indirectly affecting CepIR-regulated pathways.

bioRxiv · Sep 25, 2019Microbiology