Multiomics Analysis of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy
D. W. Van Pelt, Y. A. Kharaz, D. C. Sarver, L. R. Eckhardt, J. T. Dzierzawski, N. P. Disser, A. N. Piacentini, E. Comerford, B. McDonagh, C. L. Mendias
The paper uses multiomics analysis to study dystrophic muscles in mdx/mTR mice, finding transcriptome and proteome changes related to protein balance and metabolism, with limited agreement between transcriptome and proteome fold changes.
bioRxiv · Oct 25, 2019Physiology