Author

N. P. Disser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 4 Cell Biology· 1

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Organism:mouse· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. L. Mendias· 5 shared D. C. Sarver· 3 shared K. B. Sugg· 3 shared J. B. Swanson· 2 shared J. R. Talarek· 2 shared L. M. Martinez· 2 shared A. C. Noah· 1 shared A. J. De Micheli· 1 shared

Activity by Year

2017-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersPhysiology

C. L. Mendias

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5 papers

Recent·Most cited

Single-cell Transcriptomics Identify Extensive Heterogeneity in the Cellular Composition of Mouse Achilles Tendons

A. J. De Micheli, J. B. Swanson, N. P. Disser, L. M. Martinez, N. R. Walker, D. J. Oliver, B. D. Cosgrove, C. L. Mendias

The paper uses single-cell RNA sequencing to identify 11 cell types in mouse Achilles tendons, including three new fibroblast populations, and models cell interactions.

bioRxiv · Apr 2, 2020Cell Biology

Multiomics Analysis of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy

D. W. Van Pelt, Y. A. Kharaz, D. C. Sarver, L. R. Eckhardt, J. T. Dzierzawski, N. P. Disser, A. N. Piacentini, E. Comerford, B. McDonagh, C. L. Mendias

The paper uses multiomics analysis to study dystrophic muscles in mdx/mTR mice, finding transcriptome and proteome changes related to protein balance and metabolism, with limited agreement between transcriptome and proteome fold changes.

bioRxiv · Oct 25, 2019Physiology

Adaptive and Innate Immune Cell Responses in Tendons and Lymph Nodes After Tendon Injury and Repair

A. C. Noah, T. M. Li, L. M. Martinez, S. Wada, J. B. Swanson, N. P. Disser, K. B. Sugg, S. A. Rodeo, T. T. Lu, C. L. Mendias

This study investigates adaptive and innate immune cell responses in tendons and lymph nodes after tendon injury, finding a coordinated adaptive immune response that may regulate healing.

bioRxiv · Oct 2, 2019Physiology

Insulin-like growth factor 1 receptor signaling in tenocytes is required for adult tendon growth

N. P. Disser, K. B. Sugg, J. R. Talarek, D. C. Sarver, B. J. Rourke, C. L. Mendias

This study shows that IGF1 signaling in tenocytes is essential for postnatal tendon growth in response to mechanical loading.

bioRxiv · Jun 18, 2019Physiology

Postnatal Tendon Growth and Remodeling Requires Platelet-Derived Growth Factor Receptor Signaling

K. B. Sugg, J. F. Markworth, N. P. Disser, A. M. Rizzi, J. R. Talarek, D. C. Sarver, S. V. Brooks, C. L. Mendias

This study shows PDGFR signaling is essential for postnatal tendon growth and remodeling, with MT1-MMP mediating fibroblast migration and being regulated by PI3K/Akt and ERK1/2.

bioRxiv · Oct 25, 2017Physiology