Cancer cells resist mechanical destruction in the circulation via RhoA-myosin II axis
D. L. Moose, B. L. Krog, L. Zhao, T.-H. Kim, S. Williams-Perez, G. Burke, L. Rhodes, M. Vanneste, P. Breheny, M. Milhem, C. S. Stipp, A. C. Rowat, M. D. Henry
This study identifies the RhoA-myosin II axis as a mechanism enabling cancer cells to resist mechanical destruction by hemodynamic forces in circulation.
bioRxiv · Apr 6, 2019Cancer Biology