Author

P. Breheny

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Vanneste· 2 shared A. C. Rowat· 1 shared B. L. Krog· 1 shared B. W. Darbro· 1 shared C. A. de March· 1 shared C. A. Kaemmer· 1 shared C. Bauchle· 1 shared C. K. Maharjan· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

M. Vanneste

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Author profile →

4 papers

Recent·Most cited

RABL6A promotes pancreatic neuroendocrine tumor angiogenesis and progression in vivo

C. K. Maharjan, C. A. Kaemmer, V. P. Muniz, C. Bauchle, S. L. Mott, K. D. Zamba, P. Breheny, M. R. Leidinger, B. W. Darbro, S. Stephens, D. K. Meyerholz, D. E. Quelle

This study shows RABL6A promotes pancreatic neuroendocrine tumor angiogenesis and progression in vivo by affecting tumor formation, angiogenesis, and survival.

bioRxiv · Mar 17, 2021Cancer Biology

Locally-invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging

C. Yong, D. Moose, N. Bannick, M. Vanneste, R. Svensson, P. Breheny, J. Brown, M. Cohen, M. Henry

The paper improves a prostate cancer mouse model with a bioluminescent reporter to monitor tumor progression and shows that double knockout of Pten and Trp53 leads to castrate-resistant, locally invasive tumors.

bioRxiv · Apr 23, 2020Cancer Biology

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures

C. A. de March, W. B. Titlow, T. Sengoku, P. Breheny, H. Matsunami, T. S. McClintock

The paper identifies OR response patterns to odorants and mixtures in mice, showing common interactions that explain olfactory phenomena.

bioRxiv · Jan 15, 2020Cell Biology

Cancer cells resist mechanical destruction in the circulation via RhoA-myosin II axis

D. L. Moose, B. L. Krog, L. Zhao, T.-H. Kim, S. Williams-Perez, G. Burke, L. Rhodes, M. Vanneste, P. Breheny, M. Milhem, C. S. Stipp, A. C. Rowat, M. D. Henry

This study identifies the RhoA-myosin II axis as a mechanism enabling cancer cells to resist mechanical destruction by hemodynamic forces in circulation.

bioRxiv · Apr 6, 2019Cancer Biology