Cancer BiologybioRxivPreprint
STAG2 loss-of-function affects short-range genomic contacts and modulates urothelial differentiation in bladder cancer cells
L. Richart Gines, E. Lapi, V. Pancaldi…·F. X. Real
This study investigates how STAG2 loss-of-function affects genomic contacts and urothelial differentiation in bladder cancer cells, finding that STAG2 is critical for DNA looping that sustains luminal differentiation.