Author

L. S. McDaniel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Scasny· 3 shared J. E. Vidal· 3 shared B. Alibayov· 2 shared E. McDevitt· 2 shared A. G. Jop Vidal· 1 shared A. G. Vidal· 1 shared B. J. Akerley· 1 shared B. Jackson· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

A. Scasny

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3 papers

Recent·Most cited

Heme-Mediated Selection of Encapsulated Streptococcus pneumoniae in the Lungs by Oxidative Stress

B. Alibayov, A. G. Jop Vidal, L. Murin, A. Scasny, K. Takeshita, K. Beaton, K. Edwards, T. Punshon, B. Jackson, L. S. McDaniel, J. E. Vidal

This study shows that heme from oxidized hemoglobin promotes the selection of encapsulated Streptococcus pneumoniae in the lungs, linking oxidative stress to pneumococcal pneumonia pathogenesis.

bioRxiv · Nov 14, 2023Microbiology

Prophylactic inhibition of colonization by Streptococcus pneumoniae with the secondary bile acid metabolite deoxycholic acid

J. E. Vidal, M. N. Wier, U. Angulo-Zamudio, E. McDevitt, A. G. Vidal, B. Alibayov, A. Scasny, S. M. Wong, B. J. Akerley, L. S. McDaniel

This study shows deoxycholic acid eradicates Streptococcus pneumoniae colonization in vitro and in vivo, with no observed resistance.

bioRxiv · May 17, 2021Microbiology

Hydrogen peroxide production by Streptococcus pneumoniae results in alpha-hemolysis by oxidation of oxy-hemoglobin to met-hemoglobin

E. McDevitt, F. Khan, A. Scasny, Z. Eichembaun, L. S. McDaniel, J. E. Vidal

This paper shows that Streptococcus pneumoniae produces hydrogen peroxide, which oxidizes oxy-hemoglobin to met-hemoglobin, causing the greenish -hemolysis halo on blood agar plates, not pneumolysin.

bioRxiv · Jul 23, 2020Microbiology