Author

B. Alibayov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 3 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. E. Vidal· 5 shared A. Scasny· 4 shared A. G. Vidal· 3 shared A. G. Jop Vidal· 2 shared F. Khan· 2 shared L. Murin· 2 shared L. S. McDaniel· 2 shared P. Smith· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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5 shared papersMicrobiology

J. E. Vidal

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5 papers

Recent·Most cited

Ultrastructural, metabolic and genetic determinants of the acquisition of macrolide resistance by Streptococcus pneumoniae

X. Wu, B. Alibayov, X. Xiang, S. Lattar, F. Sakai, A. A. Medders, B. Antezana, L. Keller, A. G. Vidal, Y.-L. Tzeng, D. A. Robinson, D. Stephens, Y. Yua, J. E. Vidal

This study identifies molecular and metabolic factors that influence the acquisition of macrolide resistance in Streptococcus pneumoniae through chromosomal and ICE integration.

bioRxiv · Dec 27, 2023 · PreprintMicrobiology

Heme-Mediated Selection of Encapsulated Streptococcus pneumoniae in the Lungs by Oxidative Stress

B. Alibayov, A. G. Jop Vidal, L. Murin, A. Scasny, K. Takeshita, K. Beaton, K. Edwards, T. Punshon, B. Jackson, L. S. McDaniel, J. E. Vidal

This study shows that heme from oxidized hemoglobin promotes the selection of encapsulated Streptococcus pneumoniae in the lungs, linking oxidative stress to pneumococcal pneumonia pathogenesis.

bioRxiv · Nov 14, 2023Microbiology

Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to cytotoxicity of human lung cells

A. Scasny, B. Alibayov, F. Khan, S. Rao, L. Murin, A. G. Vidal, P. Smith, L. Wei, K. S. Edwards, K. Warncke, J. E. Vidal

This study shows that Streptococcus pneumoniae produces H2O2, which oxidizes hemoproteins like hemoglobin and cytochrome c, leading to mitochondrial dysfunction and cell death in human lung cells.

bioRxiv · Jun 7, 2023 · PreprintMicrobiology

Oxidative reactions catalyzed by hydrogen peroxide produced by Streptococcus pneumoniae and other Streptococci Cause the Release and Degradation of Heme from Hemoglobin

B. Alibayov, A. Scasny, F. Khan, A. Creel, P. Smith, A. G. Jop Vidal, F. M. Fitisemanu, T. Teresita Padilla-Benavides, J. N. Weiser, J. E. Vidal

bioRxiv · Aug 23, 2022Microbiology

Prophylactic inhibition of colonization by Streptococcus pneumoniae with the secondary bile acid metabolite deoxycholic acid

J. E. Vidal, M. N. Wier, U. Angulo-Zamudio, E. McDevitt, A. G. Vidal, B. Alibayov, A. Scasny, S. M. Wong, B. J. Akerley, L. S. McDaniel

This study shows deoxycholic acid eradicates Streptococcus pneumoniae colonization in vitro and in vivo, with no observed resistance.

bioRxiv · May 17, 2021Microbiology