Author

L. S. Xu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

R. P. DeKoter· 3 shared H. L. Raczkowski· 2 shared B. R. de Oliveira· 1 shared C. R. Batista· 1 shared H. Rysan· 1 shared J. Iansavitchous· 1 shared J. T. Zhu· 1 shared M. Astridge· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

R. P. DeKoter

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3 papers

Recent·Most cited

N-Acetylcysteine alters disease progression and increases Janus Kinase mutation frequency in a mouse model of precursor B cell acute lymphoblastic leukemia

M. P. Sams, J. Iansavitchous, M. Astridge, H. Rysan, L. S. Xu, B. R. de Oliveira, R. P. DeKoter

This study shows that N-acetylcysteine (NAC) alters disease progression in a mouse model of B-ALL by increasing Jak3 R653H mutation frequency.

bioRxiv · Oct 19, 2023Cancer Biology

Spi-C and PU.1 counterregulate Rag1 and Igκ transcription to effect immunoglobulin kappa recombination in small pre-B cells

L. S. Xu, J. T. Zhu, H. L. Raczkowski, C. R. Batista, R. P. DeKoter

bioRxiv · Dec 28, 2022 · PreprintImmunology

The E26 Transformation-Specific-family transcription factor Spi-C is dynamically regulated by external signals in B cells

H. L. Raczkowski, L. S. Xu, W. C. Wang, R. P. DeKoter

The paper investigates how external signals regulate Spi-C expression in B cells, showing that factors like lipopolysaccharide and cytokines reduce Spic levels, while some treatments partially prevent this downregulation.

bioRxiv · Aug 25, 2021Immunology