Author

R. P. DeKoter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

L. S. Xu· 3 shared H. L. Raczkowski· 2 shared B. R. de Oliveira· 1 shared C. R. Batista· 1 shared F. A. Dick· 1 shared H. Rysan· 1 shared J. Iansavitchous· 1 shared J. Rhee· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersImmunology

L. S. Xu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

N-Acetylcysteine alters disease progression and increases Janus Kinase mutation frequency in a mouse model of precursor B cell acute lymphoblastic leukemia

M. P. Sams, J. Iansavitchous, M. Astridge, H. Rysan, L. S. Xu, B. R. de Oliveira, R. P. DeKoter

This study shows that N-acetylcysteine (NAC) alters disease progression in a mouse model of B-ALL by increasing Jak3 R653H mutation frequency.

bioRxiv · Oct 19, 2023Cancer Biology

EZH2 inhibition stimulates viral mimicry in resting splenic B cells

F. A. Dick, S. J. Kim, P. K. Kiser, R. P. DeKoter

EZH2 inhibition causes repeat misexpression and B cell death by mimicking viral infection in splenic B cells.

bioRxiv · May 8, 2023 · PreprintPathology

Spi-C and PU.1 counterregulate Rag1 and Igκ transcription to effect immunoglobulin kappa recombination in small pre-B cells

L. S. Xu, J. T. Zhu, H. L. Raczkowski, C. R. Batista, R. P. DeKoter

bioRxiv · Dec 28, 2022 · PreprintImmunology

The E26 Transformation-Specific-family transcription factor Spi-C is dynamically regulated by external signals in B cells

H. L. Raczkowski, L. S. Xu, W. C. Wang, R. P. DeKoter

The paper investigates how external signals regulate Spi-C expression in B cells, showing that factors like lipopolysaccharide and cytokines reduce Spic levels, while some treatments partially prevent this downregulation.

bioRxiv · Aug 25, 2021Immunology

A role for ATP Citrate Lyase in cell cycle regulation during myeloid differentiation

J. Rhee, L. A. Solomon, R. P. DeKoter

This study shows that ATP Citrate Lyase (ACL) regulates cell cycle progression during myeloid differentiation by affecting acetyl-CoA availability for fatty acid synthesis and histone acetylation.

bioRxiv · Jan 20, 2019Immunology