New insights into the ORF2 capsid protein, a key player of the hepatitis E virus lifecycle
M. Ankavay, C. Montpellier, I. M. Sayed, J.-M. Saliou, C. Wychowski, L. Saas, S. Duvet, C.-M. Aliouat-Denis, R. Farhat, V. de Masson d'Autume, P. Meuleman, J. D. Dubuisson, L. Cocquerel
This study characterizes the glycosylation of HEV ORF2 protein and its role in viral lifecycle, showing that glycosylation does not affect particle assembly but contributes to antigenicity and nuclear translocation of ORF2i.
bioRxiv · Oct 5, 2018Microbiology