Author

L. Sacconi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:imaging· 4 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

F. Pavone· 3 shared C. Crocini· 2 shared C. Olianti· 2 shared F. Giardini· 2 shared I. Costantini· 2 shared L. Silvestri· 2 shared A. A. F. de Vries· 1 shared A. P. Di Giovanna· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersPhysiology

F. Pavone

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Optogenetic confirmation of transverse-tubular membrane excitability in intact cardiac myocytes

M. Scardigli, M. Pasek, L. Santini, C. Palandri, E. Conti, C. Crocini, M. Campione, L. Loew, A. A. F. de Vries, D. Pijnappels, F. Pavone, C. Poggesi, E. Cerbai, R. Coppini, P. Kohl, , L. Sacconi

The paper demonstrates that cardiac myocyte T-tubules can generate action potentials autonomously, distinct from those in the sarcolemma, using an all-optical method.

bioRxiv · Nov 29, 2023 · PreprintPhysiology

Precision sampling of discrete sites identified during in-vivo functional testing in the mammalian heart

D. Vermoortele, C. Olianti, M. Amoni, F. Giardini, S. De Buck, C. K. Nagaraju, R. Willems, L. Roderick, K. Sipido, L. Sacconi, P. Claus

The paper develops a 3D-printed targeted sampling method to accurately identify and study arrhythmogenic sites in the mammalian heart after myocardial infarction.

bioRxiv · Nov 29, 2023Bioengineering

3D imaging and morphometry of the heart capillary system in spontaneously hypertensive rats and normotensive controls

C. Olianti, I. Costantini, F. Giardini, E. Lazzeri, C. Crocini, C. Ferrantini, F. Pavone, P. G. Camici, L. Sacconi

This study uses 3D imaging to analyze capillary network remodeling in spontaneously hypertensive rats, finding increased density and dispersion before hypertension onset.

bioRxiv · Aug 5, 2020Physiology

KHz-rate volumetric voltage imaging of the whole zebrafish heart

L. Sacconi, L. Silvestri, E. Rodriguez, G. Armstrong, F. Pavone, A. Shrier, G. Bub

This paper introduces a new imaging method to map voltage activity in whole zebrafish hearts at KHz rates, revealing novel electrical propagation dynamics in the atrioventricular canal.

bioRxiv · Jul 13, 2020Physiology

RAPID: Real-time image-based autofocus for all wide-field optical microscopy systems

L. Silvestri, M. C. Muellenbroich, I. Costantini, A. P. Di Giovanna, L. Sacconi, F. S. Pavone

RAPID provides real-time autofocus for wide-field microscopy, enabling high-quality imaging and 3D tracking of fast-moving organisms.

bioRxiv · Jul 31, 2017Bioengineering